DCAF15 serves as a substrate recognition component in the DCX (DCAF15) complex, coordinating the ubiquitination and degradation of target proteins and may affect NK cell function and APC-NK cell interactions. Notably, arylsulfonamide anticancer drugs alter the substrate specificity of the complex, promoting ubiquitination and degradation of RBM39, RBM23, and PRPF39. DCAF15-DDB1 Protein, Human (sf9, His, Strep) is the recombinant human-derived DCAF15-DDB1 protein, expressed by sf9 insect cells , with N-Strep, N-8*His labeled tag.
