DCN1-IN-2 [CAS 2543578-57-8]

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SKU:QM-0082404

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Description
DCN1-IN-2 is a DCN1 inhibitor with an IC50 value of 2.96 nM. DCN1-IN-2 can alleviate Ang II/TGFβ-induced activation of cardiac fibroblasts. DCN1-IN-2 can reduce ISO-induced cardiac fibrosis and remodeling in mice by selectively inhibiting cullin 3[1].
CAS Number
[2543578-57-8]
Molecular Formula
C18H14ClF3N4OS
Molecular Weight
426.84
Smiles
O=C(CCN1C(NN=C1C2=CC=C(Cl)C=C2)=S)NC3=CC=CC(C(F)(F)F)=C3
Target
TGF-beta/Smad
Shipping Conditions
Room temperature

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DCN1-IN-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.