DDR1-IN-5 [CAS 2416022-90-5]

DDR1-IN-5 is a selective Discoidin Domain Receptor family, member 1 (DDR1) inhibitor with an IC50 of 7.36 nM. DDR1-IN-5 inhibits auto-phosphorylation DDR1b (Y513) with an IC50 of 4.1 nM. DDR1-IN-5 has anti-cancer activity[1]. DDR1-IN-5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

[2416022-90-5]

C22H13F3N6O

434.37

CC1=C(C#CC2=CN=C3N2N=CC=C3)C4=C(C=C1)C(NC5=CN=CC(C(F)(F)F)=C5)=NO4

Discoidin Domain Receptor

DDR1

99.65

DMSO : 2.78 mg/mL (ultrasonic; warming; heat to 60°C)

4°C (Powder, sealed storage, away from moisture and light)

Room Temperature