Dehydrocorydaline (hydroxyl)
Dehydrocorydaline (hydroxyl)
SKU:QM-0163070-01
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Product Details
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Description
Dehydrocorydaline (13-Methylpalmatine) hydroxyl is an alkaloid that regulates protein expression of Bax, Bcl-2; activates caspase-7, caspase-8, and inactivates PARP. Dehydrocorydaline hydroxyl elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities. Dehydrocorydaline hydroxyl shows strong anti-malarial effects (IC50=38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain.
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Molecular Formula
C22H25NO5
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Molecular Weight
383.44
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Smiles
CC1=C(C=CC(OC)=C2OC)C2=C[N+]3=C1C4=CC(OC)=C(OC)C=C4CC3.[OH-]
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Target
Autophagy; Bcl-2 Family; Caspase; p38 MAPK; Parasite; PARP
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Purity
99.52
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Solubility
DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Dehydrocorydaline (hydroxyl)
Dehydrocorydaline (hydroxyl) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.