Dehydrofalcarinol [CAS 36150-08-0]

Dehydrofalcarinol is a polyacetylene compound found in Desmanthodium guatemalense. Dehydrofalcarinol shows potent inhibitory activity against MDA-MB-231, MDA-MB-157, BT-549, HCC1806, MDA-MB-468 and MDA-MB-453 cells with IC50 values of 0.051, 0.059, 0.22, 0.3, 0.85 and 2.8 μM. Dehydrofalcarinol shows anticancer activity depending on 17β-hydroxysteroid dehydrogenase (17β-HSD) type 11. Dehydrofalcarinol can be used for the research of triple-negative breast cancer[1].

[36150-08-0]

C17H22O

242.36

C=CCCCCC/C=C\CC#CC#C[C@H](O)C=C

17β-HSD

Room temperature