Denbufylline [CAS 57076-71-8]

Denbufylline (BRL 30892) is an inhibitor of phosphodiesterase-4 (PDE4) . Denbufylline is able to block the degradation of intracellular cAMP (cyclic adenosine phosphate) thereby increasing the level of intracellular cAMP, which helps regulate a variety of cellular functions. Denbufylline can be used in the study of chronic obstructive pulmonary disease (COPD), asthma and other inflammatory diseases[1].

[57076-71-8]

C16H24N4O3

320.39

O=C(N1CCCC)N(CCCC)C2=C(N(CC(C)=O)C=N2)C1=O

Phosphodiesterase (PDE)

99.92

DMSO : 33 mg/mL (ultrasonic; warming)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature