DENV-IN-2 [CAS 2253675-62-4]

DENV-IN-2 is a potent dengue viral replication inhibitor extracted from patent WO2018215315A1, compound 6AB, has an EC50 of 0.016 nM. DENV-IN-2 shows high potent activity against all four serotypes of the Dengue virus with EC50s ranging from 0.013 to 0.029 nM[1].

[2253675-62-4]

C29H26ClF3N2O6

590.97

O=C([C@H]1[C@H](COC2=CC(OC)=CC(N[C@@H](C3=CC=C(Cl)C=C3)C(N4CCC5=C4C=C(OC(F)(F)F)C=C5)=O)=C2)C1)O

Dengue Virus; DNA/RNA Synthesis; Flavivirus

10 mM in DMSO

Room temperature