Deoxyviolacein [CAS 5839-61-2]

Deoxyviolacein is a bacterial metabolite and byproduct in the biosynthesis of the bisindole alkaloid violacein that has anticancer, antibacterial, and antifungal properties. It inhibits proliferation of hepatocellular carcinoma cells when used at concentrations ranging from 0.1 to 1 μM. Deoxyviolacein (125 μg/mL) has antibacterial activity against Gram-positive bacteria, including S. aureus, B. subtilis, and B. megaterium. It also has antifungal activity against R. solani when used at a concentration of 2 mg/ml.

[5839-61-2]

C20H13N3O2

327.34

O=C1NC(C=CC=C2)=C2/C1=C3C(NC(C4=CNC5=C4C=CC=C5)=C\3)=O

Bacterial; Fungal

Room temperature