Deruxtecan [CAS 1599440-13-7]

Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan and Patritumab deruxtecan (HY-P99813)[2].

[1599440-13-7]

C52H56FN9O13

1034.05

O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NCC(NCOCC(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C48)=O)=O)=O)=O)=O)=O

Drug-Linker Conjugates for ADC

Camptothecins

99.94

DMSO : 73.33 mg/mL (ultrasonic)

-20°C (Powder, protect from light, stored under nitrogen)

Blue Ice

H302, H315, H319, H335

H302, H315, H319, H335