Deruxtecan-d4 [CAS 2760715-91-9]

Deruxtecan-d4 is deuterium labeled Deruxtecan. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.

[2760715-91-9]

C52H52D4FN9O13

1038.08

O=C(C=CC1=O)N1CCCCCC(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(NC([2H])([2H])C(NCOC([2H])([2H])C(N[C@@H]3C4=C5C(C(N6C5)=CC([C@](O)(C(OC7)=O)CC)=C7C6=O)=NC8=CC(F)=C(C)C(CC3)=C84)=O)=O)=O)=O)=O)=O

Drug-Linker Conjugates for ADC; Isotope-Labeled Compounds

10 mM in DMSO

Room temperature