Desacetylvinblastine hydrazide [CAS 55383-37-4]
Desacetylvinblastine hydrazide [CAS 55383-37-4]
SKU:QM-0107851
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Product Details
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Description
Desacetylvinblastine hydrazide (Deacetylvinblastine hydrazide; DAVLBH) is an active component of EC145, a folate-targeted drug conjugate. Desacetylvinblastine hydrazide interferes with the formation of the mitotic spindle, and thus inhibits cell division and leads to cell death. Desacetylvinblastine hydrazide exhibits antitumor activity against folate receptor (FR) -positive tumor[1].
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CAS Number
[55383-37-4]
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Molecular Formula
C43H56N6O7
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Molecular Weight
768.94
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Smiles
CC[C@@]12[C@@]3([H])[C@@]4(CCN3CC=C2)C5=CC([C@@]6(C7=C(CC[N@@]8C[C@](C[C@](O)(C8)CC)([H])C6)C9=CC=CC=C9N7)C(OC)=O)=C(OC)C=C5N([C@@]4([H])[C@](O)([C@@H]1O)C(NN)=O)C
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Target
Microtubule/Tubulin
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Shipping Conditions
Room temperature
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Desacetylvinblastine hydrazide [CAS 55383-37-4]
Desacetylvinblastine hydrazide is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.