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Desmethyl Bosentan [CAS 253688-61-8]

Desmethyl Bosentan [CAS 253688-61-8]

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SKU:QM-0105358-01

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  • Description

    Desmethyl bosentan is an active metabolite of the endothelin receptor antagonist bosentan.1 Desmethyl bosentan (25 μM) activates the pregnane X receptor (PXR) in CV-1 monkey kidney cells expressing the human receptor in a reporter assay.

  • CAS Number

    [253688-61-8]

  • Molecular Formula

    C26H27N5O6S

  • Molecular Weight

    537.59

  • Smiles

    O=S(NC1=C(OC2=C(O)C=CC=C2)C(OCCO)=NC(C3=NC=CC=N3)=N1)(C4=CC=C(C(C)(C)C)C=C4)=O

  • Target

    Cytochrome P450; Drug Metabolite

  • Shipping Conditions

    Room temperature

  • Hazard Statement

    H302

  • Precautions

    P264-P270-P330-P501

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Variant Variant total Quantity Price Variant total
500 µgQM-0105358-01
500 µgQM-0105358-01
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1 mgQM-0105358-02
1 mgQM-0105358-02
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£652.64/ea
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Desmethyl Bosentan [CAS 253688-61-8]

Desmethyl Bosentan is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.