Desmethylazelastine [CAS 47491-38-3]
Desmethylazelastine [CAS 47491-38-3]
SKU:QM-0067284-01
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Product Details
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Description
Desmethylazelastine is a main active metabolite of Azelastine that is oxidatively metabolized by the cytochrome P450 enzyme system with a protein binding rate of 97% and an elimination half-life of 54 hours. Azelastine is an orally active, selective and high-affinity histamine H1-receptor antagonist. Azelastine can be used in studies of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2[1][2][3][4][5].
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CAS Number
[47491-38-3]
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Molecular Formula
C21H22ClN3O
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Molecular Weight
367.87
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Smiles
O=C1C2=C(C(CC3=CC=C(C=C3)Cl)=NN1C4CCNCCC4)C=CC=C2
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Target
Drug Metabolite
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302
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Precautions
P264-P270-P330-P501
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Desmethylazelastine [CAS 47491-38-3]
Desmethylazelastine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.