DGEM3

DGEM3 is a molecular glue degrader targeting GEMIN3 (a member of the survival of motor neuron complex) . dGEM3 can be used in the research of diseases related to abnormal protein regulation, such as cancer and neurodegenerative diseases[1].

C31H35Cl2N5O5

628.55

O=C(N[C@@H](C(C)(C)C)C(N1[C@H](C(NCC2=CC=C(C3=C(Cl)C=C(Cl)C=C3)C=C2)=O)C[C@@H](O)C1)=O)C4=C5N(N=C4)CCCO5

Molecular Glues

Room temperature