DGN549-L [CAS 1884276-68-9]

DGN549-L is a DNA alkylator and can be utilized for antibody conjugation at lysine residues. DGN549-L can be used in the synthesis of antibody-drug conjugates (ADCs) [1].

[1884276-68-9]

C58H58N8O13

1075.13

O=C(C1=C2)N3C4=CC=CC=C4C[C@@]3([H])CNC1=CC(OCC5=CC(COC(C=C(N=C[C@@]6([H])N(C7=CC=CC=C7C6)C8=O)C8=C9)=C9OC)=CC(NC([C@H](C)NC([C@H](C)NC(CCCCC(ON(C%10=O)C(CC%10)=O)=O)=O)=O)=O)=C5)=C2OC

Drug-Linker Conjugates for ADC

10 mM in DMSO

Room temperature