DHFR-IN-5-amino-PEG3-C2-azido [CAS 3077918-53-4]

DHFR-IN-5-amino-PEG3-C2-azido is a synthesized E3 ligase ligand-linker conjugate that can be used to synthesize BION106. BION106 is a potent DHFR-TS PROTAC degrader with anti-malarial activity[1].

[3077918-53-4]

C26H40N8O6

560.65

CCC1=NC(N)=NC(N)=C1OCCCOC(C=CC=C2)=C2CCC(NCCOCCOCCOCCN=[N+]=[N-])=O

E3 Ligase Ligand-Linker Conjugates

Room temperature