DHODH-IN-21 [CAS 2450341-39-4]

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SKU:QM-0068117

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Description
DHODH-IN-21 (compound 19) is an orally active selective dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 value of 1.1 nM. DHODH-IN-21 has anticancer activity and can be used in studies of acute myeloid leukaemia (AML) [1].
CAS Number
[2450341-39-4]
Molecular Formula
C20H19ClF4N6O4
Molecular Weight
518.85
Smiles
O=C1N(C2=C(F)C=C(C(NC3=C(Cl)N=CC=C3C)=O)C(O[C@@H](C)C(F)(F)F)=N2)N=C(N1CC)CO
Target
Dihydroorotate Dehydrogenase
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

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DHODH-IN-21 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.