DiABZI-Mal [CAS 2763540-24-3]

DiABZI-Mal is a STING agonist with maleimide group, which can be used for the synthesis of conjugates. diABZI-Mal activates cGAS-STING pathway to induce cytokine production such as interferon-type I. diABZI-Mal promotes maturation of DC cells and efficiently induces CD8+ T immune reaction. diABZI-Mal inhibits tumor growth[1].

[2763540-24-3]

C52H63N15O9

1042.15

O=C(N)C1=CC2=C(N(C(NC(C3=CC(C)=NN3CC)=O)=N2)C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O)=NC6=C4C(OCCCN7CCN(C(CCCCCN8C(C=CC8=O)=O)=O)CC7)=CC(C(N)=O)=C6)C(OC)=C1

STING

Room temperature