Dibenzothiophene [CAS 132-65-0]

Dibenzothiophene is an orally active and a noncompetitive CYP1A inhibitor. Dibenzothiophene inhibits CYP1A-mediated EROD activity with a Km of 0.592 μM. Dibenzothiophene interacts with the AHR pathway. Dibenzothiophene enhances the embryotoxicity of β-naphthoflavone. Dibenzothiophene shows acute toxicity in mice. Dibenzothiophene is mainly used for the study of the mechanism of developmental toxicity in organisms[1][2].

[132-65-0]

C12H8S

184.26

C12=CC=CC=C1C3=CC=CC=C3S2

Aryl Hydrocarbon Receptor; Cytochrome P450

CYP1

99.98

DMSO : 75 mg/mL (ultrasonic; warming; heat to 60°C)

4°C (Powder, protect from light)

Room Temperature

H302, H410

H302, H410