Diosbulbin C [CAS 20086-07-1]

Diosbulbin C is a diterpene lactone component, which can be extracted from traditional Chinese medicine Dioscorea bulbifera L.. Diosbulbin C possesses high anticancer activity in non-small cell lung cancer (NSCLC) . Diosbulbin C could induce cell cycle arrest at G0/G1 phase in NSCLC. Diosbulbin C also inhibits the proliferation of NSCLC cells, possibly by downregulating the expression/activation of AKT, DHFR, and TYMS[1][1].

[20086-07-1]

C19H22O7

362.37

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Akt; Dihydrofolate reductase (DHFR) ; Endogenous Metabolite

Room temperature