DKK-1 Proteinas are potent antagonists of canonical Wnt signaling, inhibiting LRP5/6-Wnt interactions and forming a ternary complex with KREMEN to promote LRP5/6 internalization. In addition to its proapoptotic function by antagonizing KREMEN1 independently of Wnt, DKK-1 also exhibits antiapoptotic activity. DKK-1 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived DKK-1 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag. The total length of DKK-1 Protein, Human (Biotinylated, HEK293, Fc-Avi) is 235 a.a., with molecular weight of 66-80 kDa.
Molecular Formula
22943 (Gene_ID) O94907 (T32-H266) (Accession)
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
