DL78 [CAS 132993-79-4]

DL78 is an effective anti-mitotic agent. DL78 induces mitotic arrest, mitotic catastrophe and apoptosis in cancer cells by disrupting the interaction between Myc and α-tubulin. DL78 exhibits broad anti-cancer activity, especially against cancer cells with chromosomal instability and excessive expression of MYC. DL78 significantly reduces tumor burden in the OV81.2 xenograft model. DL78 can be used for the study of ovarian cancer[1].

[132993-79-4]

C20H16O5

336.34

O=C(C1=C(C)OC2=CC=C(OC)C=C12)C3=CC4=CC(OC)=CC=C4O3

Apoptosis; c-Myc; Microtubule/Tubulin

Room temperature