DMeThPmR [CAS 1262032-37-0]

DMeThPmR, a ribonucleoside derivative, is a potent and selective human nucleoside transporter 1 (hCNT1) inhibitor (Ki = 0.3-0.98 μM) . dMeThPmR exhibit weak inhibitory activity on hCNT2 (IC50 = 133 μM) and hCNT3 (Ki = 32.7 μM) . dMeThPmR can protect cells from the toxicity of nucleoside drugs. dMeThPmR can be used for the research of cancer[1].

[1262032-37-0]

C12H14N2O4S

282.32

O=C1N([C@H]2C[C@H](O)[C@@H](CO)O2)C=C(C=C(C)S3)C3=N1

Nucleoside Transporters

CNT1; CNT2; CNT3

Room temperature