DMP-851 [CAS 188978-02-1]

DMP-851 is a cyclic urea HIV protease inhibitor, with a Ki of 0.021 nM. DMP-851 shows antiviral activity against laboratory strains of HIV-l and HIV-2 as well as against primary clinical isolates derived from Zidovudine -resistant samples (A018C, E, WR 10983).

[188978-02-1]

C31H37N5O3

527.66

O=C1N(CC2=CC3=C(NN=C3N)C=C2)[C@H](CC4=CC=CC=C4)[C@H](O)[C@@H](O)[C@@H](CC5=CC=CC=C5)N1CCCC

HIV; HIV Protease

HIV-1; HIV-2

Room temperature