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DMX-5804 [CAS 2306178-56-1]

DMX-5804 [CAS 2306178-56-1]

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QM-0137197-01

£228.60 GBP
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Product Details

  • Description

    DMX-5804 is a potent, orally active and selective MAP4K4 inhibitor, with an IC50 of 3 nM, a pIC50 of 8.55 for human MAP4K4, less potent on MINK1/MAP4K6 (pIC50, 8.18), and TNIK/MAP4K7 (pIC50, 7.96) . DMX-5804 enhances cardiomyocyte survival, and reduces ischemia-reperfusion injury in mice[1].

  • CAS Number

    [2306178-56-1]

  • Molecular Formula

    C21H19N3O3

  • Molecular Weight

    361.39

  • Smiles

    O=C1NC=NC2=C1C(C3=CC=C(OCCOC)C=C3)=CN2C4=CC=CC=C4

  • Target

    MAP4K

  • Isoform

    MAP4K2/GCK; MAP4K3/GLK; MAP4K4/HGK; MAP4K5/KHS1; MAP4K6/MINK1; MAP4K7/TNIK

  • Purity

    99.83

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335
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Variant Variant total Quantity Price Variant total
1 mgQM-0137197-01
1 mgQM-0137197-01
£228.60/ea		 £0.00
£228.60/ea £0.00
5 mgQM-0137197-02
5 mgQM-0137197-02
£426.65/ea		 £0.00
£426.65/ea £0.00
10 mM - 1 mLQM-0137197-03
10 mM - 1 mLQM-0137197-03
£464.31/ea		 £0.00
£464.31/ea £0.00
10 mgQM-0137197-04
10 mgQM-0137197-04
£652.64/ea		 £0.00
£652.64/ea £0.00
25 mgQM-0137197-05
25 mgQM-0137197-05
£1,047.51/ea		 £0.00
£1,047.51/ea £0.00
50 mgQM-0137197-06
50 mgQM-0137197-06
£1,467.90/ea		 £0.00
£1,467.90/ea £0.00
100 mgQM-0137197-07
100 mgQM-0137197-07
£1,970.91/ea		 £0.00
£1,970.91/ea £0.00
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DMX-5804 [CAS 2306178-56-1]

DMX-5804 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.