DNA Gyrase-IN-1 [CAS 3031486-11-7]

DNA Gyrase-IN-1 (compound 42) is a potent and selective DNA gyrase inhibitor with an IC50 value of 2.6 µM. DNA Gyrase-IN-1 has high inhibitory activity against Mycobacterium tuberculosis (Mtb) with MIC of 0.49 µM. DNA Gyrase-IN-1 can be used for researching tuberculosis[1].

[3031486-11-7]

C24H24FN7O6

525.49

C[C@@H]1N([C@@H](CN2C3=C(C4=C(C=C3CC5([C@]21[H])C(NC(NC5=O)=O)=O)C(OC[C@H]6NC(CC6)=O)=NO4)F)C)C#N

Bacterial; DNA/RNA Synthesis

10 mM in DMSO

Room temperature