DNA-PK-IN-3 [CAS 2734846-19-4]

DNA-PK-IN-3 is a potent inhibitor of DNA-PK. DNA-PK-IN-3 synergistically enhances the effect of radiotherapy and chemotherapy and effectively inhibits tumor growth. DNA-PK-IN-3 also effectively reduces the damage to normal cells and reducing side effects. DNA-PK-IN-3 has the potential for the research of cancer disease (extracted from patent WO2021213460A1, compound 4) [1].

[2734846-19-4]

C19H19N9O

389.41

CC1=CC2=NC=NN2C=C1NC3=NC=C4C(N(C5CCOCC5)C6=NC=CN64)=N3

DNA-PK

10 mM in DMSO

Room temperature