Dnp-RPLALWRS [CAS 172666-82-9]

Dnp-RPLALWRS is a fluorescent peptide substrate designed for human matrilysin (MMP-7) . After enzymatic cleavage of Dnp-RPLALWRS at the alanine-leucine bond, the release of the Dnp group alleviates fluorescence quenching, thereby enabling real-time quantitative analysis of MMP-7 activity by increasing tryptophan emission. Dnp-RPLALWRS provides a sensitive and efficient detection method for kinetic studies and inhibitor screenin[1].

[172666-82-9]

C52H77N17O14

1164.27

OC[C@@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CC(C)C)NC([C@H]3N(C([C@H](CCCNC(N)=N)NC4=CC=C([N+]([O-])=O)C=C4[N+]([O-])=O)=O)CCC3)=O)=O)=O)=O)=O)=O

Fluorescent Dye

10 mM in DMSO

Room temperature