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Dot1L-IN-9

Dot1L-IN-9

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SKU:QM-0130196

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  • Description

    Dot1L-IN-9 (Compound 12) is a DOT1L inhibitor (IC50: 125 nM) . Dot1L-IN-9 reduces H3K79 dimethylation. Dot1L-IN-9 can be used for anti-leukemia research[1].

  • Molecular Formula

    C28H38N8O3

  • Molecular Weight

    534.65

  • Smiles

    NC1=C2N=CN(C2=NC=N1)[C@@H]3O[C@H](CN4CCC(CCC5=NC6=CC(C(C)(C)C)=CC=C6N5)CC4)[C@@H](O)[C@H]3O

  • Target

    Histone Methyltransferase

  • Isoform

    DOT1L

  • Shipping Conditions

    Room temperature

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Dot1L-IN-9

Dot1L-IN-9 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.