DOTA-ADIBO (TFA)

DOTA-ADIBO TFA is a DOTA-derived bifunctional chelator (BFC) that allows drug conjugation via an uncatalyzed, copper-free cycloaddition reaction. DOTA-ADIBO TFA enables the construction of fusion chelator systems that can be further used to synthesize radiotracers after Cu[64] modification. Positron emission tomography imaging of tumors expressing integrin αvβ6[1].

C36H43F3N6O10

776.76

OC(CN1CCN(CC(O)=O)CCN(CC(NCCC(N2C3=C(C#CC4=C(C2)C=CC=C4)C=CC=C3)=O)=O)CCN(CC(O)=O)CC1)=O.O=C(O)C(F)(F)F

Integrin

αvβ6

99.06

DMSO : 100 mg/mL (ultrasonic)

-20°C (Powder, protect from light, stored under nitrogen)

Blue Ice