DOTA-ALB-01

DOTA-ALB-01 is an albumin-bound FAP inhibitor (FAPI) ligand. DOTA-ALB-01 labeled with 68Ga or 177Lu has a high FAP-binding affinity and enhanced tumor uptake and retention. DOTA-ALB-01 can be used for PET/CT and SPECT/CT imaging of cancers, especially late-stage cancers[1].

C67H98F2N12O18

1397.56

O=C(NCCCCC(C(NC1=CC=CC2=C1N=CC=C2C(NCC(N3CC(C[C@H]3C#N)(F)F)=O)=O)=O)NC(C(C4=CC=C(C=C4)CC(C)C)C)=O)CCOCCOCCOCCOCCOCCOCCNC(CN5CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC5)=O

FAP

Room temperature