DOTA-ALB-02

DOTA-ALB-02 is an albumin-bound FAP inhibitor (FAPI) ligand. DOTA-ALB-02 labeled with 177Lu has a high FAP-binding affinity and enhanced tumor uptake and retention with a significant tumor/nontarget ratio. DOTA-ALB-02 can be used for PET/CT and SPECT/CT imaging of cancers, especially late-stage cancers[1].

C64H91F2IN12O18

1481.38

O=C(NCCCCC(C(NC1=CC=CC2=C1N=CC=C2C(NCC(N3CC(C[C@H]3C#N)(F)F)=O)=O)=O)NC(CCCC4=CC=C(I)C=C4)=O)CCOCCOCCOCCOCCOCCOCCNC(CN5CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC5)=O

FAP

Room temperature