DOTA-FAPT

DOTA-FAPT is a novel targeting FAP tracer. DOTA-FAPT can be radiolabeled with gallium-68 and lutetium-177. DOTA-FAPT can be used for PET imaging studies of cancer-associated fibroblasts[1].

C67H96F2N16O26

1579.57

O=C(COCCOCCNC([C@H](CC(O)=O)NC([C@H](CC(O)=O)NC([C@@H](NC(CN1CCN(CCN(CCN(CC1)CC(O)=O)CC(O)=O)CC(O)=O)=O)CCC(N[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)NC(C)=O)=O)=O)=O)=O)N3CCN(CCCOC4=CC=C(C5=C4)N=CC=C5C(NCC(N6CC(F)(C[C@]6(C#N)[H])F)=O)=O)CC3

Radionuclide-Drug Conjugates (RDCs)

Room temperature