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DOV-216,303 [CAS 86215-36-3]

DOV-216,303 [CAS 86215-36-3]

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QM-0126650

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Product Details

  • Description

    DOV-216,303 is an antidepressant compound. DOV-216,303 inhibits the reuptake of norepinephrine (NE), serotonin (5‐HT), and dopamine (DA), with IC50 values of 14 nM, 20 nM and 78 nM for hSERT, hNET and hDAT, respectively. DOV-216,303 increases monoamine release in the prefrontal cortex of olfactory bulbectomized (OBX) rats[1][2][3].

  • CAS Number

    [86215-36-3]

  • Molecular Formula

    C11H12Cl3N

  • Molecular Weight

    264.58

  • Smiles

    ClC1=C(C=C(C23CC2CNC3)C=C1)Cl.Cl

  • Target

    Dopamine Transporter; Serotonin Transporter

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

  • Hazard Statement

    H301-H319

  • Precautions

    P264-P270-P280-P330-P405-P501
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DOV-216,303 [CAS 86215-36-3]

DOV-216,303 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.