Doxofylline [CAS 69975-86-6]
Doxofylline [CAS 69975-86-6]
SKU:QM-0157367-01
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Product Details
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Description
Doxofylline is an orally active PDE IV inhibitor and A1AR antagonist. Doxofylline reduces inflammation in epithelial cells via inhibiting mitochondrial ROS production and amelioration of multiple cellular pathways (NLRP3-TXNIP inflammasome activation) . Doxophylline can be used in studies of asthma, chronic obstructive pulmonary disease, and bronchospasm[1][2][3].
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CAS Number
[69975-86-6]
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Molecular Formula
C11H14N4O4
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Molecular Weight
266.25
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Smiles
O=C(N1C)N(C)C2=C(N(CC3OCCO3)C=N2)C1=O
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Target
Adenosine Receptor; Phosphodiesterase (PDE) ; Reactive Oxygen Species (ROS)
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Purity
99.97
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Solubility
DMSO : 50 mg/mL (ultrasonic) |H2O : 25 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302
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Precautions
H302
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Doxofylline [CAS 69975-86-6]
Doxofylline is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.