DQP-1105 [CAS 380560-89-4]

DQP-1105 is a potent noncompetitive NMDA receptor antagonist. DQP-1105 inhibits GluN2C- and GluN2D-containing receptors (IC50=7.0 and 2.7 μM, respectively) . The IC50 values are at least 50-fold lower than those for recombinant GluN2A-, GluN2B-, GluA1-, or GluK2-containing receptors[1].

[380560-89-4]

C29H24BrN3O4

558.42

O=C(CCC(N1N=C(CC1C2=CC=C(C=C2)Br)C3=C(C4=CC=CC=C4)C5=C(C=CC(C)=C5)NC3=O)=O)O

IGluR

NMDA Receptor

98

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

4°C (Powder, stored under nitrogen)

Room Temperature

H302, H315, H319, H335

H302, H315, H319, H335