DS17701585 [CAS 2983027-66-1]

DS17701585 (Compound 11) is a highly selective, orally active EP300 and CBP inhibitor with IC50 values of 0.040, 0.15, 0.45 and 0.70 µM against CBP, EP300, H3K27 and SOX2. DS17701585 can be used for cancer research[1].

[2983027-66-1]

C24H26N4O5S

482.55

O=C([C@@H](C1)N(C(C2(C3=CC=C(OC)C=C3)CCCC2)=O)CS1(=O)=O)NC4=CC=CC5=C4C=NN5

Histone Acetyltransferase; Histone Demethylase

CBP/p300

10 mM in DMSO

Room temperature