Name: DS18561882 [CAS 2227149-22-4]
Brand: QuantiMol
SKU: QM-0143139-01
Price: 226.18 GBP
Availability: InStock

Product Details

Description
DS18561882 is a highly potent, isozyme-selective methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor with an IC50 value of 0.0063 μM. DS18561882 also has inhibitory effect on MTHFD1 (IC50=0.57 μM) . DS18561882 exhibits a good oral pharmacokinetic profile[1].
CAS Number
[2227149-22-4]
Molecular Formula
C28H31F3N4O6S
Molecular Weight
608.63
Smiles
CS(=O)(NC1=CC=C(C(N2CCC(C3=CC=C(N4C[C@H](C)N(C)CC4)C(C)=C3O5)=C(C5=O)C2)=O)C=C1OC(F)(F)F)=O
Target
Methylenetetrahydrofolate Dehydrogenase (MTHFD)
Purity
99.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Storage Conditions
4°C (Powder, stored under nitrogen)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
1 mgQM-0143139-01	1 mgQM-0143139-01 £226.18/ea	£0.00	Quantity	£226.18/ea	£0.00

5 mgQM-0143139-02	5 mgQM-0143139-02 £489.83/ea	£0.00	Quantity	£489.83/ea	£0.00

10 mM - 1 mLQM-0143139-03	10 mM - 1 mLQM-0143139-03 £672.08/ea	£0.00	Quantity	£672.08/ea	£0.00

10 mgQM-0143139-04	10 mgQM-0143139-04 £740.12/ea	£0.00	Quantity	£740.12/ea	£0.00

25 mgQM-0143139-05	25 mgQM-0143139-05 £1,292.94/ea	£0.00	Quantity	£1,292.94/ea	£0.00

50 mgQM-0143139-06	50 mgQM-0143139-06 £2,121.57/ea	£0.00	Quantity	£2,121.57/ea	£0.00

100 mgQM-0143139-07	100 mgQM-0143139-07 £2,873.66/ea	£0.00	Quantity	£2,873.66/ea	£0.00

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DS18561882 [CAS 2227149-22-4]

DS18561882 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.