DS20362725 [CAS 2735803-20-8]

DS20362725 is an estrogen-related receptor α (ERRα) agonist. DS20362725 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) with an IC50 value of 0.6 μM. DS20362725 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM) [1].

[2735803-20-8]

C19H22N2O2

310.39

OC1=CC=C(OC2=CC=C3N=C(C)N(C)C3=C2)C=C1C(C)(C)C

Estrogen Receptor/ERR

ERRα

99.34

DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature