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DSR-141562 [CAS 2007975-22-4]

DSR-141562 [CAS 2007975-22-4]

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SKU:QM-0145645-01

£527.50 GBP
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  • Description

    DSR-141562 is a novel, orally active, and selective brain-penetrant phosphodiesterase 1 (PDE1) inhibitor. DSR-141562 shows preferential selectivity for human PDE1B with an IC50 of 43.9 nM, and the IC50 values for human PDE1A and 1C are 97.6 and 431.8 nM, respectively. DSR-141562 can be used for the study of positive symptoms, negative symptoms and cognitive impairments associated with schizophrenia[1][2].

  • CAS Number

    [2007975-22-4]

  • Molecular Formula

    C19H25F3N4O3

  • Molecular Weight

    414.42

  • Smiles

    O=C1N(C)C(OC[C@H]2CC[C@H](C(F)(F)F)CC2)=NN3C1=CN=C3C4CCOCC4

  • Target

    Phosphodiesterase (PDE)

  • Isoform

    PDE1

  • Purity

    99.98

  • Solubility

    DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0145645-01
5 mgQM-0145645-01
£527.50/ea
£0.00
£527.50/ea £0.00
10 mM - 1 mLQM-0145645-02
10 mM - 1 mLQM-0145645-02
£574.88/ea
£0.00
£574.88/ea £0.00
10 mgQM-0145645-03
10 mgQM-0145645-03
£865.26/ea
£0.00
£865.26/ea £0.00
25 mgQM-0145645-04
25 mgQM-0145645-04
£1,556.60/ea
£0.00
£1,556.60/ea £0.00
50 mgQM-0145645-05
50 mgQM-0145645-05
£2,497.01/ea
£0.00
£2,497.01/ea £0.00
100 mgQM-0145645-06
100 mgQM-0145645-06
£3,815.28/ea
£0.00
£3,815.28/ea £0.00

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DSR-141562 [CAS 2007975-22-4]

DSR-141562 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.