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DTHIB [CAS 897326-30-6]

DTHIB [CAS 897326-30-6]

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SKU:QM-0146237-01

£118.38 GBP
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  • Description

    DTHIB is a direct and selective heat shock factor 1 (HSF1) inhibitor with a Kd of 160 nM for DTHIB binding to the HSF1 DNA binding domain (DBD) . DTHIB inhibits HSF1 cancer gene signature (HSF1 CaSig) and selectively stimulates degradation of nuclear HSF1. DTHIB has potently anticancer activities and can be used for prostate cancer research[1].

  • CAS Number

    [897326-30-6]

  • Molecular Formula

    C13H9ClFN3O3

  • Molecular Weight

    309.68

  • Smiles

    O=C(NC1=CC=C(F)C=C1)NC2=CC=C(Cl)C([N+]([O-])=O)=C2

  • Target

    HSP

  • Concentration

    10mM

  • Purity

    99.82

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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Variant Variant total Quantity Price Variant total
5 mgQM-0146237-01
5 mgQM-0146237-01
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10 mM - 1 mLQM-0146237-02
10 mM - 1 mLQM-0146237-02
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10 mgQM-0146237-03
10 mgQM-0146237-03
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25 mgQM-0146237-04
25 mgQM-0146237-04
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50 mgQM-0146237-05
50 mgQM-0146237-05
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100 mgQM-0146237-06
100 mgQM-0146237-06
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DTHIB [CAS 897326-30-6]

DTHIB is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.