DTME [CAS 71865-37-7]

DTME (dithio-bis-maleimidoethane) is a homobifunctional, maleimide crosslinker specifically designed for conjugation between sulfhydryl groups (-SH). DTME, whose molecular structure consists of two maleimide groups connected by an ethylene disulfide bridge, can specifically react with thiol - containing molecules (such as cysteine residues) to form stable covalent bonds. DTME allows crosslinks that can be cleaved with reducing agents such as DTT. DTME is commonly utilized to explore and characterize protein structure, particularly oligomerization, or protein interactions[1].

[71865-37-7]

C12H12N2O4S2

312.36

O=C(C=C1)N(CCSSCCN2C(C=CC2=O)=O)C1=O

Biochemical Assay Reagents

10mM

99.03

DMSO : 50 mg/mL (ultrasonic)

-20°C, 3 years (Powder)

Blue Ice

H302+H312+H332, H315, H319, H335

H302+H312+H332, H315, H319, H335