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SKU:QM-0143467-01
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Duocarmycin DM, a DNA minor-groove alkylator, is an antibody agent conjugates (ADCs) toxin. Duocarmycin DM is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity[1][2].
C28H27ClF3N3O5
577.98
OC1=C2C(C=CC=C2)=C3C(N(C[C@H]3CCl)C(C4=CC5=C(N4)C=CC(OCCN(C)C)=C5)=O)=C1.OC(C(F)(F)F)=O
ADC Payload; DNA Alkylator/Crosslinker
Daunorubicins/Doxorubicins
99.15
10 mM in DMSO
-20°C (Powder, sealed storage, away from moisture)
Blue Ice
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Duocarmycin DM is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.