DV1

DV1 is a selective antagonist for CXC chemokine receptor 4 (CXCR4) . DV1 exhibits antiviral activity by blocking HIV-1 entry through the CXCR4 co-receptor. DV1 is stable in rat plasma and exhibits good pharmacokinetic characteristics in rat models[1].

C108H170N34O26S2

2424.85

O=C(NCC(N[C@H](C)C(N[C@H](CO)C(N[C@H](CC1=CNC2=CC=CC=C12)C(N[C@H](CC3=CNC=N3)C(N[C@H](CCCNC(N)=N)C(N4[C@@H](CCC4)C(N[C@H](CC(O)=O)C(N[C@H](CCCCN)C(N[C@H](CS)C(N[C@H](CS)C(N[C@H](CC(C)C)C(NCC(N[C@H](CC5=CC=C(C=C5)O)C(N[C@H](CCC(N)=O)C(N[C@H](CCCCN)C(N[C@H](CCCNC(N)=N)C(N6[C@@H](CCC6)C(N[C@H](CC(C)C)C(N7[C@H](CCC7)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H](CC(C)C)N

CXCR; HIV

Room temperature