DWIZ-1

DWIZ-1 is a potent WIZ molecular glue degrader. dWIZ-1 recruitments WIZ (ZF7) to cereblon (CRBN) induces WIZ degradation. dWIZ-1 has the potential for the research of sickle cell disease (SCD) [1].

C22H29N3O4

399.48

O=C([C@@H](N(CC1=C2C=CC(O[C@@H]([C@@H]3N(CC)CCCC3)C)=C1)C2=O)CC4)NC4=O

Histone Acetyltransferase; Molecular Glues

98

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature