Dyrk1A-IN-12 [CAS 2243701-11-1]

Dyrk1A-IN-12 (compound S43) is a Dyrk (Dual specificity tyrosine phosphorylation regulated kinase 1A inhibitor. Dyrk1A-IN-12 inhibits Dyrk1A with a IC50 of 95 nM. Dyrk1A-IN-12 shows anti-EV-A71 activity with an EC50 of 4.4 μM, CC50 of 12.8 μM and SI of 2.9. Dyrk1A-IN-12 shows potent inhibition against herpes simplex virus (HSV) [1].

[2243701-11-1]

C22H16FN3O2S

405.44

O=C(C1=CC(OC)=CC=C1F)NC2=CN=CC(C3=CC(C4=CC=CN=C4)=CS3)=C2

DYRK; Enterovirus

DYRK1

Room temperature