(E) -2,6-Di-tert-butyl-4- (4- (diethylamino) styryl) pyrylium (trifluoromethanesulfonate) [CAS 2811663-45-1]
(E) -2,6-Di-tert-butyl-4- (4- (diethylamino) styryl) pyrylium (trifluoromethanesulfonate) [CAS 2811663-45-1]
SKU:QM-0011273
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Product Details
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Description
(E) -2,6-Di-tert-butyl-4- (4- (diethylamino) styryl) pyrylium (trifluoromethanesulfonate) (Compound 4a) is a Gram-negative outer membrane permeabilizer with synergistic antibacterial activity through the blockage on LptA/LptC interaction via targeting Met47 in LptA. (E) -2,6-Di-tert-butyl-4- (4- (diethylamino) styryl) pyrylium (trifluoromethanesulfonate) potentiates pol B against both wild-typed and MDR A. baumannii and E. coli strains. (E) -2,6-Di-tert-butyl-4- (4- (diethylamino) styryl) pyrylium (trifluoromethanesulfonate) can be used as antibiotic adjuvants against MDR Gram-negative bacteria[1].
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CAS Number
[2811663-45-1]
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Molecular Formula
C26H36F3NO4S
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Molecular Weight
515.63
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Smiles
O=S(C(F)(F)F)([O-])=O.CCN(CC)C(C=C1)=CC=C1/C=C/C2=CC(C(C)(C)C)=[O+]C(C(C)(C)C)=C2
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Target
Bacterial
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Shipping Conditions
Room temperature
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(E) -2,6-Di-tert-butyl-4- (4- (diethylamino) styryl) pyrylium (trifluoromethanesulfonate) [CAS 2811663-45-1]
(E) -2,6-Di-tert-butyl-4- (4- (diethylamino) styryl) pyrylium (trifluoromethanesulfonate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.