EAPB 02303 is a microtubule-disrupting agent and inhibitor. EAPB 02303 induces mitosis arrest and impairment of spindle assembly. Thus, EAPB 02303 induces apoptosis and exhibits antitumor activity. EAPB 02303 also exhibits a potent synergy with Paclitaxel at lower concentrations[1].
CAS Number
[1958290-51-1]
Molecular Formula
C17H14N4O2
Molecular Weight
306.32
Smiles
OC(C=C1)=C(O)C=C1C2=CN=C3C(NC)=NC4=CC=CC=C4N32
Target
Apoptosis; Microtubule/Tubulin; Mitosis
Purity
98.05
Solubility
H2O : 30 mg/mL (ultrasonic; warming; heat to 60°C)
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)