EBL-3183 [CAS 2872672-18-7]

EBL-3183, an indole-2-carboxylate, is a potent metallo-β-lactamase (MBL) inhibitor. EBL-3183 is reversibly binding, non-covalent, competitive NDM-1 inhibitor with a pIC50 of 7.7[1].

[2872672-18-7]

C25H27FN4O6S

530.57

C[C@H](N1C[C@]2(OC1=O)C[C@@H](C2)CN)C3=CC=CC4=C3NC(C(O)=O)=C4C5=CC=C(C(F)=C5)NS(C)(=O)=O

Bacterial; Beta-lactamase

10 mM in DMSO

Room temperature