EBOV/MARV-IN-3 [CAS 2687245-05-0]

EBOV/MARV-IN-3 (compound 32) is a potent EBOV and MARV inhibitor with IC50 values of 0.5, 1.2 µM, respectively. EBOV/MARV-IN-3 binds to the hydrophobic pocket close to EBOV Y517. EBOV/MARV-IN-3 shows antiviral activity[1].

[2687245-05-0]

C27H29F3N2O6

534.52

CC1=C(C(OC2=CC(OCC(CN3CCC(CC3)C(N)=O)O)=CC=C21)=O)CC4=CC=C(C=C4)OC(F)(F)F

Filovirus

EBOV; MARV

10 mM in DMSO

Room temperature